Case report: Necrotizing pancreatitis after SAE

Splenic artery embolization (SAE) is a relatively safe, effective, and commonly...Read more on AuntMinnie.comRelated Reading: Case report: TAE for life-threatening hemobilia Case report: Interventional retrieval of portacath fragment
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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The efficacy of some therapeutic methods (open surgical debridement (OSD), conservative treatment (CST) and minimally invasive drainage (MID)) for severe acute pancreatitis (SAP) and moderately severe acute pa...
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Tags: Research article Source Type: research
ConclusionBased on the patient ’s medical history and all the examination results, it was possible to make a diagnosis of primary APS and, starting from diagnosis of thrombocytopenia, we were allowed to conclude that all of manifestation were epi-phenomena of a unique clinical entity, rather than unrelated diseases. Though APS is one of the most common thrombocytophilias, unfortunately, it is not recognized often enough. The lack of prevention in undiagnosed patients may cause severe complications which can in turn result in the death of those patients.
Source: Autoimmunity Highlights - Category: Allergy & Immunology Source Type: research
ConclusionsThis study provided an overall picture of ICI-induced vitiligo in daily medical practice on a large number of pharmacovigilance observations of case patients. Among the observations of ICI-induced vitiligo, the diagnosed cancer was melanoma for almost all patients. Most patients in the study experienced other associated adverse drug reactions (ADRs), such as colitis, pruritus, hypothyroidism, hyperthyroidism, thyroiditis, pancreatitis, and gastritis. Furthermore, our data suggest that the resolution of pembrolizumab- or nivolumab-induced vitiligo could be a marker of disease progression. Future studies evaluatin...
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research
Conditions:   Pancreatitis, Calcific;   Pancreatitis, Chronic Intervention:   Device: single operator video cholangioscopy Sponsor:   Evangelisches Krankenhaus Düsseldorf Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: Our study is the first to report that endoscopic therapy of PFCs using LAMS is safe and effective even in a community hospital setting with limited resources and support compared to large academic centers. PMID: 31615198 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
This study focused on the underlying mechanisms of gut barrier dysfunction in rats induced by aggressive fluid resuscitation in SAP. This study further indicated the important role of necroptosis in intestinal barrier injury which could be relieved by using necroptosis-specific inhibitor Nec-1 before aggressive fluid resuscitation, thus reducing intestinal barrier damage. We also found pancreas damage after intestinal ischemia/reperfusion challenge and indicated the effects of high mobility group protein B1 in the vicious cycle between SAP and intestinal barrier damage.
Source: Shock - Category: Emergency Medicine Tags: Online Articles Source Type: research
CONCLUSIONS: Our data indicate that the genetic architecture and natural history of FCS and MCS are different. FCS expressed the most severe clinical phenotype as determined by resistance to triglyceride-lowering medications and higher incidence of acute pancreatitis episodes. The most common genetic abnormality underlying FCS was represented by biallelic mutation in LPL while APOA5 variants, in combination with high rare polygenic burden, were the most frequent genotype of MCS. PMID: 31619059 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - Category: Cardiology Authors: Tags: Arterioscler Thromb Vasc Biol Source Type: research
​BY FAHAD SHAH &AHMED RAZIUDDIN, MDA 68-year-old woman presented with acute abdominal pain that had started three hours earlier. She said she had constant upper abdominal pain that was sharp and stabbing, and she rated her pain as 8/10.The patient said the pain did not radiate, and she was clearly in acute distress. She reported that her last meal had been four hours before and that she was nauseated and had had three to four episodes of dry heaves.She had no other concerning symptoms, and her pain was unaffected by eating, drinking, or position. She had a paraesophageal rolling hiatal hernia and was aware of her chr...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
ConclusionTo our knowledge, this is the first report of diffuse histology-proven MCN of the pancreas.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
AbstractUse of open abdomen (OA) progressively acquired increasing importance with the diffusion of the damage control management of critical patients. The purpose of the present study is to identify the state of the art about the use of OA in Italy, focusing on techniques, critical issues and clinical outcomes. A prospective analysis of adult patients enrolled in the IROA, limited to the Italian participating centres was performed. 375 patients were enrolled. Mean age was 64  ± 16 years old, 56% of the patients were male, mean BMI was 26.9 ± 5.2. Main indications for using OA...
Source: Updates in Surgery - Category: Surgery Source Type: research
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