Lead (Pb) in Alzheimer's Dementia: A Systematic Review of Human Case-control Studies.

CONCLUSION: The available case-control studies are insufficient to draw conclusions about the role of Pb in AD. Most methods do not capture long-term or early-life exposure. The preferred measure of chronic Pb is in bone, which has not been utilized in case-control AD studies. Future research should measure bone Pb in AD, together with other biomarkers, such as amyloid and tau imaging, and markers of cerebrovascular pathology.
PMID: 30854970 [PubMed - as supplied by publisher]

Source: Current Alzheimer Research - March 9, 2019 Category: Neurology Authors: Brown EE, Shah P, Pollock BG, Gerretsen P, Graff-Guerrero A Tags: Curr Alzheimer Res Source Type: research