RFX1 downregulation contributes to TLR4 overexpression in CD14+ monocytes via epigenetic mechanisms in coronary artery disease

Toll-like receptor 4 (TLR4) expression is increased in activated monocytes, which play a critical role in the pathogenesis of coronary artery disease (CAD). However, the mechanism remains unclear. Regulatory f...

Source: Clinical Epigenetics - March 11, 2019 Category: Research Authors: Pei Du, Keqin Gao, Yu Cao, Shuang Yang, Yang Wang, Ren Guo, Ming Zhao and Sujie Jia Tags: Research Source Type: research