Validated Reference Panel from renewable source of genomic DNA available for standardization of blood group genotyping
Extended blood group genotyping is an invaluable tool used for prevention of alloimmunization. Genotyping is particularly suitable when antigens are weak, specific antisera are unavailable, or accurate phenotyping is problematic due to a disease state or recent transfusions. Additionally, genotyping facilitates establishment of mass-scale patient-matched donor databases. However, standardization of genotyping technologies has been hindered by the lack of reference panels. A well-characterized renewable reference panel for standardization of blood group genotyping was developed.
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Evgeniya Volkova, Emilia Sippert, Meihong Liu, Teresita Mercado, Gregory A. Denomme, Orieji Illoh, Zhugong Liu, Maria Rios, Collaborative Study Group Tags: Regular Article Source Type: research