Complete response of renal cell carcinoma vena cava tumor thrombus to neoadjuvant immunotherapy

ConclusionsPreoperative immunotherapy with nivolumab and ipilimumab for locally advanced clear cell renal cancer resulted in a complete response of an extensive vena cava tumor thrombus, which enabled curative-intent resection of a non-responding primary tumor. If validated in larger cohorts, preoperative immunotherapy for locally advanced renal cell carcinoma may ultimately impact surgical planning and long-term prognosis.
Source: Journal for Immunotherapy of Cancer - Category: Cancer & Oncology Source Type: research