Algorithm builds model of Alzheimer's brain changes

Researchers used an online image analysis algorithm called volBrain with MRI...Read more on AuntMinnie.comRelated Reading: Deep-learning MRI algorithm aids in neurological diagnoses AI algorithm predicts Alzheimer's disease progression AI could bring ultralow-dose imaging to amyloid PET Deep-learning algorithm predicts Alzheimer's disease AI helps uncover clues for Alzheimer's disease in MRI data
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Brain maps based on functional MRI (fMRI) scans are proving useful in predicting...Read more on AuntMinnie.comRelated Reading: Can MRI of healthy brains explain head trauma damage? Advanced MRI technique confirms dementia risk PET, MRI show physical activity aids brain health MRI links brain region to dementia, auditory deterioration DTI-MRI offers window into Alzheimer's risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
In conclusion, a polypharmacology approach of combining established, prolongevity drug inhibitors of specific nodes may be the most effective way to target the nutrient-sensing network to improve late-life health. Deletion of p38α in Neurons Slows Neural Stem Cell Decline and Loss of Cognitive Function in Mice https://www.fightaging.org/archives/2019/10/deletion-of-p38%ce%b1-in-neurons-slows-neural-stem-cell-decline-and-loss-of-cognitive-function-in-mice/ Researchers here provide evidence for p38α to be involved in the regulation of diminished neural stem cell activity with age. It is thought...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Abstract Detection of glutathione in human serum is of great importance for clinical diagnosis of various diseases, such as AIDS, diabetes mellitus, Alzheimer disease and cancer. In this work, a new water-soluble bismacrocyclic polyamine-derived compound, namely L, which contains two molecules of 4-nitro-1,2,3-benzoxa-diazole as the fluorophores, was designed and prepared. The experiments of selectivity of L toward metal ions showed it could rapidly and sensitively detect Hg2+ with a detection limit of 27 nM. Furthermore, the cell imaging and co-staining experiments in HeLa cells demonstrated that the L-Hg2+ pro...
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research
Conclusion: Subjective hearing loss was not found to be associated with significantly different dementia neuropathology, which counters hypotheses on hearing loss causing permanent neurodegeneration and cognitive decline. Hearing aid users were found to have a lower prevalence of dementia for similar levels of neurodegeneration, suggesting a potential neuroprotective effect of hearing aids.
Source: Otology and Neurotology - Category: ENT & OMF Tags: SENSORINEURAL HEARING LOSS AND TINNITUS Source Type: research
OBJECTIVE: To examine the association between hearing aids (HAs) and time to diagnosis of Alzheimer disease (AD) or dementia, anxiety or depression, and injurious falls among adults, aged 66 years and older, within 3 years of hearing loss (HL) diagnosis. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
FRIDAY, Sept. 6, 2019 -- Use of hearing aids is associated with lower risks for being diagnosed with Alzheimer disease, dementia, depression, anxiety, and injurious falls among elderly adults diagnosed with hearing loss, according to a study...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Older adults who use hearing aids may be less likely to develop depression, anxiety, and dementia for at least three years after a hearing loss diagnosis compared with those who do not begin using hearing aids, according to astudy published Wednesday in theJournal of the American Geriatrics Society. In addition, these individuals appear less likely to get injured in a fall.“By providing enhanced hearing input, HAs [hearing aids] may facilitate greater social engagement, lower levels of effort to recognize sounds and speech, lower levels of depression or anxiety symptoms, higher levels of physical balance, and greater...
Source: Psychiatr News - Category: Psychiatry Tags: Alzheimer's anxiety dementia depression fall injury geriatric psychiatry health insurance hearing aid hearing loss Medicare Source Type: research
Abstract Bryostatins are a class of naturally occurring macrocyclic lactones with a unique fast developing portfolio of clinical applications, including treatment of AIDS, Alzheimer's disease and cancer. This comprehensive account summarizes the recent progress (2014-present) in the development of bryostatins, including their total synthesis and biomedical applications. An emphasis is placed on the discussion of bryostatin 1, the most-studied analog to date. This review highlights the synthetic and biological challenges of bryostatins and provides an outlook on their future development. PMID: 31479550 [PubMed...
Source: Chemistry - Category: Chemistry Authors: Tags: Chemistry Source Type: research
...Mom is, for the most part, a good caregiver, but she’s resentful about what happened, and why wouldn’t she be? She has a right to these feelings except that her resentment shows through to Dad through her body language as well the tone of her voice, and from my observation, this increases Dad’s anxiety. Read the full article on HealthCentral to learn more about how our body language can affect those who we care for: Support a caregiver or jump-start discussion in support groups with real stories - for bulk orders of Minding Our Elders e-mail Carol         &...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Photo credit Mari Lezhava Shadowing is terribly sad on two fronts. It is an outward expression of the fear that the person with Alzheimer’s is suffering from and it’s smothering for the caregiver who finds it difficult to have a moment alone. The behavior can occur anytime, but for those who are prone to sundowning, which is another type of anxiety-related behavior, shadowing can precede it. Learn more on about shadowing and the causes on HealthCentral: Support a caregiver or jump-start discussion in support groups with real stories - for bulk orders of Minding Our Elders e-mail Carol    &n...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
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