Outpatient cervical ripening by nitric oxide donors for prolonged pregnancy: a randomized controlled trial.

CONCLUSION: Outpatient cervical ripening with vaginal isosorbide mononitrate for prolonged pregnancy in nulliparous women does not reduce cesarean delivery rate.
CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00930618.
LEVEL OF EVIDENCE: : I.
PMID: 25415159 [PubMed - in process]

Source: Obstetrics and Gynecology - November 27, 2014 Category: OBGYN Authors: Schmitz T, Fuchs F, Closset E, Rozenberg P, Winer N, Perrotin F, Verspyck E, Azria E, Carbonne B, Lepercq J, Maillard F, Goffinet F, Groupe de Recherche en Obstétrique et Gynécologie (GROG) Tags: Obstet Gynecol Source Type: research