Hormone Therapy Linked to Slight Rise in Alzheimer's Risk

Title: Hormone Therapy Linked to Slight Rise in Alzheimer's RiskCategory: Health NewsCreated: 3/7/2019 12:00:00 AMLast Editorial Review: 3/8/2019 12:00:00 AM
Source: MedicineNet Womens Health General - Category: OBGYN Source Type: news

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Authors: Vegeto E, Villa A, Della Torre S, Crippa V, Rusmini P, Cristofani R, Galbiati M, Maggi A, Poletti A Abstract Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous system (CNS) with still unknown etiology. Several factors were hypothesized to be involved in the pathogenesis of these diseases including genetic and environmental factors. Many of these diseases show a sex prevalence and sex steroids where shown to have a role in the progression of specific forms of neurodegeneration. Estrogens were reported to be neuroprotective though their action on cognate nuclear and membran...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
(University of Pennsylvania School of Medicine) A Penn study of more than 150,000 men with prostate cancer shows androgen deprivation therapy was associated with a higher likelihood of developing dementia when compared to patients who were not exposed to the treatment.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Androgen deprivation therapy for prostate cancer is associated with an increased risk of Alzheimer ’s disease and other forms of dementia.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Alzheimer ' s Disease Prostate Cancer Dementia Hormones Source Type: news
Title: Does Hormone Therapy for Prostate Cancer Raise Dementia Risk?Category: Health NewsCreated: 5/5/2019 12:00:00 AMLast Editorial Review: 5/6/2019 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news
In this study, we found that senescent chondrocytes isolated from OA patients secrete more EVs compared with nonsenescent chondrocytes. These EVs inhibit cartilage ECM deposition by healthy chondrocytes and can induce a senescent state in nearby cells. We profiled the miR and protein content of EVs isolated from the synovial fluid of OA joints from mice with SnCs. After treatment with a molecule to remove SnCs, termed a senolytic, the composition of EV-associated miR and protein was markedly altered. The senolytic reduced OA development and enhanced chondrogenesis, and these were attributable to several specific differenti...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Vincenzo Tigano1, Giuseppe Lucio Cascini2, Cristina Sanchez-Castañeda3, Patrice Péran4 and Umberto Sabatini5* 1Department of Juridical, Historical, Economic and Social Sciences, University of Magna Graecia, Catanzaro, Italy 2Department of Experimental and Clinical Medicine, University of Magna Graecia, Catanzaro, Italy 3Department of Clinical Psychology and Psychobiology, University of Barcelona, Barcelona, Spain 4ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, Toulouse, France 5Department of Medical and Surgical Sciences, University of Magna Graecia, Catanzaro, Ita...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
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