Polymorphisms of human glucocorticoid receptor gene in systemic lupus erythematosus: a single-centre result

ConclusionThe increased and decreased sensitivity associated withGR BclI and A3669G polymorphisms could have a pathogenic significance in SLE especial with the central nervous system and psychiatric symptoms. Improving our knowledge on the importance ofGR polymorphisms may reveal their pathophysiologic and therapeutic consequences.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research