The significance of cytokine-producing B cells in breast tumor-draining lymph nodes

ConclusionsOur data indicate that the cytokine profiles of B cells in TDLNs of patients with breast cancer show associations with various disease parameters. TNFhi and IL-10+ B cells correlated positively with indicators of a good prognosis. Further functional studies are required to elucidate the role of cytokine production by B cells in immunity against breast cancer.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research