Omics and anaesthesia: pharmacogenomics, proteomics and metabolomics

Publication date: Available online 8 March 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Thomas E.F. Walton, Jonathan N. RajanAbstractThe inter-individual response to medications and the presence of genetic polymorphisms which impact the safe conduct of anaesthesia and analgesia are of paramount importance to the anaesthetist, intensivist and pain physician. The frequency of these phenomena is not reflected in the attention afforded them in undergraduate or postgraduate curricula. In order to appreciate how these issues may affect our clinical practice, it is crucial to have a working understanding of the concepts that underpin the relevant fields within the collection of disciplines we term the ‘omics’.
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research