Galectin-3 is Essential for IgE-Dependent Activation of Human Basophils by A549 Lung Epithelial Cells

Using novel co-culture model systems, galectin-3 is shown to facilitate basophil secretion of IL-4/IL-13, with implications that this unique mode of activation may be linked to a variety of diseases ranging from asthma to cancer.

Source: Journal of Allergy and Clinical Immunology - March 7, 2019 Category: Allergy & Immunology Authors: John T. Schroeder, Abiodun A. Adeosun, Danh Do, Anja P. Bieneman Source Type: research