A Validated Scale for Assessing the Severity of Acute Infectious Mononucleosis

To develop a scale for the severity of mononucleosis.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Original Articles Source Type: research

Related Links:

Myalgic encephalomyelitis, also referred to as chronic fatigue syndrome (ME/CFS) is a debilitating disease characterized by myalgia and a sometimes severe limitation of physical activity and cognition. It is exacerbated by physical and mental activity. Its cause is unknown, but frequently starts with an infection. The eliciting infection (commonly infectious mononucleosis or an upper respiratory infection) can be more or less well diagnosed. Among the human herpesviruses (HHV-1-8), HHV-4 (Epstein-Barr virus; EBV), HHV-6 (including HHV-6A and HHV-6B) and HHV-7, have been implicated in the pathogenesis of ME/CFS. It was ther...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We describe a case of a 22-year-old male with STH during acute mononucleosis infection that presented with active bleeding from the right tonsil.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Visual Diagnosis in Emergency Medicine Source Type: research
Infectious mononucleosis is a common condition occurring in athletic training rooms. Most cases are due to Epstein-Barr virus infections (upward of 90%). Although treatment generally consists of symptomatic care, there is clinical variation in laboratory workup leading to diagnosis and in the method of return to play decision making. The authors suggest a systematic approach to laboratory evaluation and return to play decisions to minimize clinical variation. The most feared complication of infectious mononucleosis is potential splenic rupture. There have been several examples of the successful use of serial ultrasonograph...
Source: Clinics in Sports Medicine - Category: Sports Medicine Authors: Source Type: research
Abstract CD4+ T cells are essential for immune protection against viruses, yet their multiple roles remain ill-defined at the single-cell level in humans. Using HLA class II tetramers, we studied the functional properties and clonotypic architecture of EBV-specific CD4+ T cells in patients with infectious mononucleosis, a symptomatic manifestation of primary EBV infection, and in long-term healthy carriers of EBV. We found that primary infection elicited oligoclonal expansions of TH1-like EBV-specific CD4+ T cells armed with cytotoxic proteins that responded immediately ex vivo to challenge with EBV-infected B cel...
Source: Journal of Immunology - Category: Allergy & Immunology Authors: Tags: J Immunol Source Type: research
Publication date: Available online 11 July 2019Source: IDCasesAuthor(s): Burke A. Cunha, Nonso Osakwe
Source: IDCases - Category: Infectious Diseases Source Type: research
Marshall Thomas, 16, of Suffolk, Virginia, was diagnosed with B-cell acute lymphoblastic leukemia on Saturday in Colorado after doctors previously believe he had mononucleosis.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
-- Swollen lymph nodes often occur after exposure to bacteria or viruses, says Mayo Clinic. Common triggers include: Strep throat. Measles. Ear infection. An abscessed tooth. Mononucleosis. Skin infection. To diagnose what might be causing your...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in “Luigi Vanvitelli” University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infecti on was higher in patients about 5 years old, while serop...
Source: Intervirology - Category: Virology Source Type: research
General practitioners encounter the vast majority of patients with Epstein-Barr virus-related disease, i.e. infectious mononucleosis in children and adolescents. With the expanding knowledge regarding the mult...
Source: BMC Family Practice - Category: Primary Care Authors: Tags: Review Source Type: research
Mononucleosis syndromes are most commonly caused by infection with either Epstein-Barr virus or cytomegalovirus. There are differences in their clinical presentation and means of acquisition. Both viruses establish lifelong latency. They are associated with inducing some degree of immunosuppression potentially resulting in reactivation of the second “infecting” virus. There are few reports of suspected dual infections, and it is serologically difficult to prove. We wish to describe 2 cases of mononucleosis for which the serologic evidence for dual infection is presented. We also wish to review the serologic tes...
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research
More News: Glandular Fever (infectious mononucleosis) | Pediatrics