Variation in Transcutaneous Bilirubin Nomograms across Population  Groups

Some degree of jaundice appears in the first postnatal days in the majority of infants born at ≥35 weeks of gestation.1,2 Usually the jaundice is mild and self-limited and may even be beneficial. In unusual cases, the result of lack of equilibrium between the bilirubin production and elimination processes, the serum total bilirubin may continue to rise.3 If untreated, extreme hyperbilirubi nemia may lead to bilirubin neurotoxicity (kernicterus spectrum disorder). Not surprisingly, acute bilirubin encephalopathy, death, choreoathetotic cerebral palsy, sensorineural hearing loss, and other manifestations of bilirubin neurotoxicity still occur in developing countries with inadequate me dical resources, or in regions affected by the ravages of war.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Commentary Source Type: research

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ConclusionsWe confirmed the genetic diagnosis of mevalonic aciduria caused by MVK deficiency which had been masked by liver disease and the possible misdiagnosis of alpha-1-antitrypsin deficiency.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
AbstractHyperbilirubinemia is a common occurrence in neonates; it may be physiological or pathological. Conjugated hyperbilirubinemia may result from medical or surgical causes, and can result in irreversible liver damage if untreated. The aim of imaging is the timely diagnosis of surgical conditions like biliary atresia and choledochal cysts. Abdominal ultrasound is the first line imaging modality, and Magnetic resonance cholangiopancreatography (MRCP) also has a role, especially in pre-operative assessment of choledochal cysts (CDCs). For biliary atresia, the triangular cord sign and gallbladder abnormalities are the two...
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Journal of Perinatology, Published online: 16 August 2019; doi:10.1038/s41372-019-0439-1Sixty years of phototherapy for neonatal jaundice – from serendipitous observation to standardized treatment and rescue for millions
Source: Journal of Perinatology - Category: Perinatology & Neonatology Authors: Source Type: research
ConclusionDelayed cord clamping in term and preterm infants was a simple, safe, and effective delivery procedure, which should be recommended, but the optimal cord clamping time remained controversial.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
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Source: Annals of Surgery - Category: Surgery Tags: PAPERS OF THE 139TH ASA ANNUAL MEETING Source Type: research
The leaves and bark of Syringa oblata Lindl are used as folk medicine which has heat-clearing, detoxifying, dampness-removing and jaundice-relieving effects. There are many studies about leaves of S. oblata becau...
Source: Chemistry Central Journal - Category: Chemistry Authors: Tags: Research article Source Type: research
AbstractBackgroundHypothyroidism with impairment of renal function and raised creatinine phosphokinase (CPK) is described in adults and children with acquired hypothyroidism, but not in congenital hypothyroidism.Case presentationA male infant born at term weighing 3390  g was seen aged 2 months with prolonged jaundice. Examination showed somnolence, umbilical hernia, enlarged fontanelles and lower limb edema; length 55 cm (−1.5 SD), weight 5.4 kg (−0.13 SD). Biochemistry showed fT4 
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
In conclusion, oxidative stress can be a possible explanation of hepatic damage induced by chronic therapy with chlorpheniramine maleate and cetirizine hydrochloride.l-Carnitine has prominent hepatoprotective effects on chlorpheniramine maleate – and cetirizine hydrochloride–induced hepatic damage possibly through improvement of hepatic function and decreasing oxidative stress.
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research
Publication date: Available online 13 August 2019Source: Journal of Neonatal NursingAuthor(s): Pascalin Tiam Kapen, Youssoufa Mohamadou, Foutse Momo, Dongmeza Koudjou Jauspin, Nenkam Kanmagne, Dongmeza Dongmo JordanAbstractThis paper aims to develop an automatic neonatal incubator equipped with phototherapy, biometric fingerprint reader, remote monitoring and heart rate control modules for developing countries due to the lack of neonatal incubators. The proposed device consists of an acquisition module that senses temperatures (of the enclosure and the baby) and humidity, a biometric fingerprint reader to identify the user...
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Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
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