Decreased expression of folate transport proteins in oral cancer

The purpose of this study was to assess the expression of the 3 major folate transporters —folate receptors (FRs), reduced folate carrier (RFC), and proton-coupled folate transporter (PCFT)—in oral squamous cell carcinoma (OSCC). We hypothesized that patterns of expression of folate transporters would be different in OSCC compared with normal oral epithelium.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - March 6, 2019 Category: ENT & OMF Authors: Joanna Goral, Kayla Cuadros, Lenore Pitstick, Alice Meyer, Bruno Correia Jham, Eduardo Pereira Guimaraes, Jo ão Adolfo Costa Hanneman, Jacalyn M. Green Source Type: research