Millions of women who take HRT pills may face a greater risk of Alzheimer's, warns study

An estimated one million women in Britain and five per cent of women over the age of 50 in the US take hormone replacement therapy to help relieve menopause symptoms.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Research, published in theThe BMJ, suggests that HRT treatment for menopause may slightly increase a women’s risk of developing Alzheimer’s disease.News Weeks
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
' For women in early menopause with bothersome vasomotor symptoms, no compelling evidence exists of cognitive concern from randomized trials,'but'concerns about longer-term use'remain, say experts.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Diabetes & Endocrinology News Source Type: news
THURSDAY, March 7, 2019 -- Many women turn to hormone therapy to ease some of the more troubling symptoms of menopause, such as hot flashes and night sweats. But new research suggests that relief may come at a cost -- an increased risk of...
Source: - Daily MedNews - Category: General Medicine Source Type: news
The risk is very low and drugs to treat menopause symptoms are safe and effective, doctors say.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
Although historically considered two distinct entities, both vascular dementia (VD) and Alzheimer's Dementia (AD) are associated with increased odds of cerebrovascular disease. While early-onset AD (
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Poster Number: EI - 16 Source Type: research
Flortaucipir-PET scans have revealed increased levels of tau tangles in a key...Read more on AuntMinnie.comRelated Reading: Alzheimer's biomarkers could affect races differently Is menopause a good time to treat women for Alzheimer's? Quantitative PET better estimates amyloid plaque burden Flortaucipir-PET targets tau for Alzheimer's diagnoses PiB-PET study strengthens link between amyloid, dementia
Source: Headlines - Category: Radiology Source Type: news
In this study, we examined the benefits of early-onset, lifelong AET on predictors of health, inflammation, and cancer incidence in a naturally aging mouse model. Lifelong, voluntary wheel-running (O-AET; 26-month-old) prevented age-related declines in aerobic fitness and motor coordination vs. age-matched, sedentary controls (O-SED). AET also provided partial protection against sarcopenia, dynapenia, testicular atrophy, and overall organ pathology, hence augmenting the 'physiologic reserve' of lifelong runners. Systemic inflammation, as evidenced by a chronic elevation in 17 of 18 pro- and anti-inflammatory cytokin...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
lli D Abstract Circulating ceramide levels are abnormally elevated in age-dependent pathologies such as cardiovascular diseases, obesity and Alzheimer's disease. Nevertheless, the potential impact of age on plasma ceramide levels has not yet been systematically examined. In the present study, we quantified a focused panel of plasma ceramides and dihydroceramides in a cohort of 164 subjects (84 women) 19 to 80 years of age. After adjusting for potential confounders, multivariable linear regression analysis revealed a positive association between age and ceramide (d18:1/24:0) (β (SE) = 5.67 (2.38); p = .0198) a...
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
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Source: Menopause - Category: OBGYN Tags: Editorials Source Type: research
Conclusions: In a general population of postmenopausal women, association between poor metabolic profile with reduction in cognitive performance is more apparent in women who carry an ApoE4 allele. These data indicate a window of opportunity for interventions to reverse the trajectory of the preclinical phase of Alzheimer's disease.
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
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