Emergence of Candida auris in Russia

We report emergence of Candida auris infections in an intensive care unit of a Moscow hospital. 49 cases were diagnosed in 2016-2017; risk factors and anti-fungal susceptibilities are described. The 30-day all-cause mortality for 19 bloodstream infections, in which patients did not receive appropriate antifungal therapy, was 42.1%. Phylogenetic analysis of ITS, D1-D2 regions and K143R substitution in the ERG11 gene indicated the studied C. auris strains to be of South Asian origin. This first reported series of C. auris infections in Russia demonstrates the rapid dissemination of this species and the necessity for international surveillance and control measures.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research