Body Fat Estimation in Kidney Transplant Recipients: Skinfolds Thickness Compared With Dual-Energy X-Ray Absorptiometry
The aim of the study was to compare the method of estimating the body fat percentage (BF%) by skinfold thickness to dual-energy X-ray absorptiometry (DEXA) in kidney transplant recipients.
This study suggests that: adult RTR sarcopenia prevalence varies according to the diagnostic criteria; low muscle mass, low muscle function and low physical performance are common conditions; body adiposity association with sarcopenia depends on the criteria used to define this syndrome; and FNIH criteria detected higher adiposity in individuals with sarcopenia. PMID: 31551095 [PubMed - as supplied by publisher]
CONCLUSIONS: Sclerostin levels were low in our osteoporotic patients;therefore, sclerostin may not be a contributing factor to osteoporosis development. Because sclerostin is an osteocyte-derived peptide, its serum levels only reflect total osteocyte number and bone mass. PMID: 31526333 [PubMed - as supplied by publisher]
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
In conclusion the prevalence of B12 deficiency in KTR was estimated as 14% and was associated with reduced intake of B12 as well as higher adiposity, especially in women, and with the use of MMF. PMID: 31280734 [PubMed - as supplied by publisher]
This study included 32 patients with SSNS who had not received GC treatment in the last 6 months and a control group of 20 healthy children. Serum levels of calcium, phosphate, alkaline phosphatase, 25-(OH)D, and parathyroid hormone (PTH) were measured. BMD was determined in the lumbar spinal region using dual-energy X-ray absorptiometry (DEXA). Serum 25-(OH)D levels were lower in the SSNS patients than in the healthy children (P
CONCLUSIONS: Bone turnover decreased over time both in patients remaining on dialysis and in kidney transplant recipients. Bone mineral density and bone biomarkers were not associated with bone metabolism changes detected in bone biopsy specimens. PMID: 31088851 [PubMed - as supplied by publisher]
Conditions: Non-Alcoholic Fatty Liver Disease; Chronic Kidney Diseases; PreDiabetes; Kidney Transplant Interventions: Diagnostic Test: MR spectroscopy of the liver; Diagnostic Test: Fibroscan of the liver; Device: Continuous glucose monitoring (CGM) for four days.; Diagnostic Test: Oral glucose tolerance test (OGTT); Diagnostic Test: Intra venous glucose infusion (IIGI); Radiation: Dua l Energy X-ray Absorptiometry (DEXA) scan; Biological: Blood samples;...
Kidney transplant recipients are at increased risk of fractures. This prospective observational study investigated whether areal bone mineral density (aBMD) as assessed by dual-energy x-ray absorptiometry can predict incident fragility fractures in de novo kidney transplant recipients and whether bone turnover markers increase diagnostic accuracy. Parameters of bone mineral metabolism including parathyroid hormone (PTH), fibroblast growth factor 23, sclerostin, calcidiol and calcitriol, and bone turnover markers were assessed in blood samples collected immediately prior to kidney transplantation in 518 adult recipients.