Down-Regulation of Renal Klotho Expression by Shiga Toxin 2
Conclusion: Shiga toxin 2 treatment stimulated Tnfα transcription, down-regulated renal klotho expression and increased FGF23 formation, effects presumably contributing to renal tissue injury.Kidney Blood Press Res 2014;39:441-449
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research
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