Extracellular fluid volume expansion uncovers a natriuretic action of GLP-1: a functional GLP-1-renal axis in man.

CONCLUSIONS: In volume loaded subjects, GLP-1 induces significant natriuresis, likely brought about via a tubular mechanism secondary to suppression of ANG II, independent of renal hemodynamics, supporting the existence of a GLP-1-renal axis. PMID: 30835273 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30835273?dopt=Abstract

Source: The Journal of Clinical Endocrinology and Metabolism - March 4, 2019 Category: Endocrinology Authors: Asmar A, Cramon PK, Simonsen L, Asmar M, Sorensen CM, Madsbad S, Moro C, Hartmann B, Jensen BL, Holst JJ, Bülow J Tags: J Clin Endocrinol Metab Source Type: research