High density lipoprotein function is reduced in patients affected by genetic or idiopathic hypogonadism.

CONCLUSION(S): In hypogonadal patients pro-atherogenic lipoprotein-associated changes are associated with lower cholesterol efflux and increased influx, thus offering an explanation for a potentially increased CV risk.
PMID: 30835274 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - March 4, 2019 Category: Endocrinology Authors: Adorni MP, Zimetti F, Cangiano B, Vezzoli V, Bernini F, Caruso D, Corsini A, Sirtori CR, Cariboni A, Bonomi M, Ruscica M Tags: J Clin Endocrinol Metab Source Type: research