Dedicated breast CT shows promise for cancer screening

A dedicated breast CT scanner that features a photon-counting detector produces...Read more on AuntMinnie.comRelated Reading: Can AI enhance the utility of breast conebeam CT? UC Davis signs licensing agreement for breast CT Photon-counting breast CT shows promise Breast CT tops mammography for microcalcifications Dedicated breast CT offers promise as mammography adjunct
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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AbstractBackgroundThe density of tumor-infiltrating lymphocytes (TIL) is a predictive factor for response to neoadjuvant systemic therapy (NAST) in breast cancer. High TIL density correlates with higher complete pathologic remission (pCR) in triple negative and HER2 positive breast cancer. Additionally, not only TIL density but also subsets of immune cells in tumor stroma seem to play an important role in cancer and immune cell interaction and response to chemotherapy. Our aim is to determine TIL density and expression of CD 20, CD3, CD8, PD-L1, FOXP3 and PGM1 on core biopsy specimen and find a correlation with pCR.Trial d...
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
ConclusionConventional BC-imaging modalities have both advantages and limitations. When utilized in combination, they are often complementary. For example, a limitation of mammography is low sensitivity in dense breasts. The addition of DBT lessens this limitation by providing three-dimensional (3D) images of the breast that minimizes the effect of overlying breast tissue. Additionally, US added to mammography in dense breasts increases screening sensitivity and has the advantages of accessibility and lack of ionizing radiation. MRI is currently the most sensitive method used for detecting BC. When MRI is not suitable for ...
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research
ConclusionsA novel system using supine MRI images co-registered with intraoperative optical scanning and tracking enabled tumors to be resected with a trend toward a lower positive margin rate compared with wire-localized partial mastectomy. Margin positivity was more likely when imaging underestimated pathologic tumor size.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
This article presents a novel and completely automated algorithm for the detection of microcalcification clusters in a mammogram. A multiscale 2D non-linear energy operator is proposed for enhancing the contrast between the microcalcifications and the background. Several texture, shape, intensity, and histogram of oriented gradients (HOG) –based features are used to distinguish microcalcifications from other brighter mammogram regions. A new majority class data reduction technique based on data distribution is proposed to counter data imbalance problem. The algorithm is able to achieve 100% sensitivity with 2.59, 1.7...
Source: Journal of Digital Imaging - Category: Radiology Source Type: research
iCAD, a company based in Nashua, New Hampshire, won European CE Mark approval for its ProFound AI for 2D Mammography software system. The product relies on a “high-functioning, deep learning” artificial intelligence algorithm to a...
Source: Medgadget - Category: Medical Devices Authors: Tags: Ob/Gyn Radiology Surgery Source Type: blogs
The visibility of screen-detected cancers is generally equal to or higher on...Read more on AuntMinnie.comRelated Reading: Can DBT replace FFDM? SBI: DBT users aren't implementing synthesized 2D Synthesized 2D mammography works just as well as FFDM Breast tissue seems less dense on DBT scans Synthesized 2D mammo + DBT works for breast screening
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
AbstractPurposeTo develop a multiparametric [18F]FDG positron emission tomography/magnetic resonance imaging (PET/MRI) model for breast cancer diagnosis incorporating imaging biomarkers of breast tumors and contralateral healthy breast tissue.MethodsIn this prospective study and retrospective data analysis, 141 patients (mean 57  years) with an imaging abnormality detected on mammography and/or ultrasound (BI-RADS 4/5) underwent combined multiparametric [18F]FDG PET/MRI with PET/computed tomography and multiparametric MRI of the breast at 3  T. Images were evaluated and the following were recorded: for the tumor,...
Source: European Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Source Type: research
This article originally appeared on South Manchester Radiology here.
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Artificial Intelligence Health Tech Health Technology AI Clinical Decision Support image detection Radiology Rizwan Malik Source Type: blogs
ConclusionTOL methodology allowed effective training of both groups of readers. The iterative nature of individual training ensured production of user-friendly materials including frequently-asked-questions sheets. It allowed for each person to feel that their views were fully listened to and incorporated into the training package, allowing for training materials with high face validity.
Source: European Journal of Radiology Open - Category: Radiology Source Type: research
Objectives The purpose of this work is to present the data obtained from the first clinical in vivo application of a new dedicated spiral breast computed tomography (B-CT) equipped with a photon-counting detector. Materials and Methods The institutional review board approved this retrospective study. Twelve women referred for breast cancer screening were included and underwent bilateral spiral B-CT acquired in prone position. Additional sonography was performed in case of dense breast tissue or any B-CT findings. In 3 women, previous mammography was available for comparison. Soft tissue (ST) and high-resolution (HR) i...
Source: Investigative Radiology - Category: Radiology Tags: Original Articles Source Type: research
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