Bone Marrow Transplant Renders Second Patient Free Of HIV

British doctors report the apparent eradication of HIV from a patient who was undergoing treatment for cancer. It's only the second time this has been accomplished, despite many attempts.(Image credit: SCIENCE SOURCE)
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news

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Authors: Mohan N, Edmonds KP, Ajayi TA, Atayee RS Abstract Tramadol is a schedule IV, monoaminergic and μ-opioid-receptor analgesic with unique pharmacology properties. Though it is well established and widely utilized, there is little guidance on tramadol's place in therapy, including tolerability, safety and monitoring guidelines. Retrospective chart review of 250 patients who received oral tramadol during their hospitalization from January 1, 2018 to December 31, 2018. Of the 250 patients, 10.8% had cancer as their primary diagnosis while 8.8% were admitted for hematologic reasons. 79.1% of patients had acute...
Source: Journal of Pain and Palliative Care Pharmacotherapy - Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
Conclusion: Our study identifies C5a/C5aR1 signaling as a vital immunomodulatory program in CRC tumorigenesis and suggests a feasible preventive strategy.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
This article presents a case study of a patient receiving a bone marrow transplantation who experienced psychological distress during hospitalization because of social isolation. The National Comprehensive Cancer Network guidelines for distress management are used as a framework to outline a nursing plan of care for managing social isolation-related psychological distress in patients who are hospitalized during a worldwide pandemic. PMID: 32945803 [PubMed - as supplied by publisher]
Source: Clinical Journal of Oncology Nursing - Category: Nursing Authors: Tags: Clin J Oncol Nurs Source Type: research
oix D Abstract In Europe, two CAR T-cell products, tisagenlecleucel (Kymriah™) and axicabtagene ciloleucel (Yescarta™), were approved in 2018. While these treatments are available for use, allogeneic hematopoietic stem cell transplantation centers still need to set up a dedicated care process inspired by established procedures in the field. In order to determine necessary resources and actors, each step of the CAR T-cell care process must be planned in advance. This process, implemented by the center's coordinating nurse, should be able to be adapted to each center's needs. The purpose of this workshop...
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions The CCI is a useful metric to document performance improvement across a broad range of domains, regardless of cancer type. By the use of quality improvement science, progressive reduction in CCI has occurred over a 3-year period.
Source: Journal of Patient Safety - Category: Health Management Tags: Original Articles Source Type: research
Journal of Child and Adolescent Psychopharmacology, Ahead of Print.
Source: Journal of Child and Adolescent Psychopharmacology - Category: Pediatrics Authors: Source Type: research
nman Fleischman Electronic cigarettes (E-cigs) generate nicotine containing aerosols for inhalation and have emerged as a popular tobacco product among adolescents and young adults, yet little is known about their health effects due to their relatively recent introduction. Few studies have assessed the long-term effects of inhaling E-cigarette smoke or vapor. Here, we show that two months of E-cigarette exposure causes suppression of bone marrow hematopoietic stem and progenitor cells (HSPCs). Specifically, the common myeloid progenitors and granulocyte-macrophage progenitors were decreased in E-cig exposed animals ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
CONCLUSIONS: Our results suggest that PAI-2 deficiency increases susceptibility to spontaneous tumorigenesis in the mouse, and demonstrate that SerpinB2 expression derived from a non-hematopoietic compartment is a key host factor in the regulation of tumor growth in both the B16 melanoma and Lewis Lung carcinoma models. PMID: 32780555 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Tags: J Thromb Haemost Source Type: research
(University of Arizona Health Sciences) A potentially safer, more effective chemotherapy treatment for patients with blood-related cancers, such as leukemia, who need a particular bone marrow transplant procedure is under study at the University of Arizona Health Sciences. The procedure is known as a haploidentical (half-matched) bone marrow transplantation, or " haplo-BMT, " providng an alternate source of stem cells for patients needing a bone marrow transplant but unable to find a perfect or near-perfect donor match for human leukocyte antigens.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
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