Evaluation myocardial fibrosis in diabetes with cardiac magnetic resonance T1-mapping: correlation with the high-level hemoglobin A1c

Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide, which leads to myocardial dysfunction and even heart failure in long-term follow-up[1 –3]. The potential pathomechanism of diabetic myocardial damage is multifactorial and result in diffuse myocardial fibrosis [4,5]. Myocardial fibrosis is related to the pathogenesis of left ventricle hypertrophy and has been confirmed in the middle or later stage of diabetic cardialmyopathy, which paly an important role in cardiac structure change and the abnormality of cardiac function[67].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research