Understanding differences in allergen immunotherapy products and practices in North America and Europe

Allergen immunotherapy (AIT) is thought to be clinically effective and safe in treating allergic rhinitis, asthma, and stinging insect allergy in Europe and North America. However, there are intercontinental differences in AIT therapeutic products in terms of their application and regulation. In North America unmodified standardized and nonstandardized aqueous aeroallergen extracts are approved and used almost exclusively for subcutaneous immunotherapy, whereas more product options are available in Europe, including adsorbed allergens, chemically modified allergens, or both.

Source: Journal of Allergy and Clinical Immunology - February 28, 2019 Category: Allergy & Immunology Authors: Vera Mahler, Robert E. Esch, J örg Kleine-Tebbe, William J. Lavery, Greg Plunkett, Stefan Vieths, David I. Bernstein Tags: Reviews and feature article Source Type: research