Low-dose rt-PA may not decrease the incidence of symptomatic intracranial haemorrhage in patients with high risk of symptomatic intracranial haemorrhage.

CONCLUSIONS: Our study suggests that low-dose intravenous rt-PA for high-risk sICH stroke in Chinese patients may not decrease the incidence of sICH, and concomitant with a poor outcome compared to standard-dose rt-PA. ABBREVIATIONS: rt-PA: recombinant tissue plasminogen activator; AIS: acute ischemic stroke; sICH: symptomatic intracranial haemorrhage. PMID: 30822264 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30822264?dopt=Abstract

Source: Neurological Research - March 5, 2019 Category: Neurology Tags: Neurol Res Source Type: research