Bicycloheptylamine-Doxorubicin Conjugate: Synthesis and Anticancer Activities in σ2 Receptor-Expressing Cell Lines.

CONCLUSION: The conjugation of target bicycloheptylamines with cytotoxic moieties may yield potent and selective molecules for detection and/or treatment of certain cancers.
PMID: 30827254 [PubMed - as supplied by publisher]

Source: Medicinal Chemistry - February 28, 2019 Category: Chemistry Authors: Alamri MA, Ates-Alagoz Z, Adejare A Tags: Med Chem Source Type: research