Bone mineral density, bone turnover markers, and  incident fractures in de novo kidney transplant recipients

Kidney transplant recipients are at increased risk of fractures. This prospective observational study investigated whether areal bone mineral density (aBMD) as assessed by dual-energy x-ray absorptiometry can predict incident fragility fractures in de novo kidney transplant recipients and whether bone turnover markers increase diagnostic accuracy. Parameters of bone mineral metabolism including parathyroid hormone (PTH), fibroblast growth factor 23, sclerostin, calcidiol and calcitriol, and bone turnover markers were assessed in blood samples collected immediately prior to kidney transplantation in 518 adult recipients.

Source: Kidney International - March 3, 2019 Category: Urology & Nephrology Authors: Pieter Evenepoel, Kathleen Claes, Bjorn Meijers, Micha ël R. Laurent, Bert Bammens, Maarten Naesens, Ben Sprangers, Hans Pottel, Etienne Cavalier, Dirk Kuypers Tags: Clinical Investigation Source Type: research