Comparison of clinical characteristics of human metapneumovirus and respiratory syncytial virus infection in hospitalized young children.

Comparison of clinical characteristics of human metapneumovirus and respiratory syncytial virus infection in hospitalized young children. Jpn J Infect Dis. 2019 Feb 28;: Authors: Taniguchi A, Kawada JI, Go K, Fujishiro N, Hosokawa Y, Maki Y, Sugiyama Y, Suzuki M, Tsuji T, Hoshino S, Muramatsu H, Kidokoro H, Kinoshita F, Hirakawa A, Takahashi Y, Sato Y, Natsume J Abstract Human metapneumovirus (HMPV) infection and respiratory syncytial virus (RSV) infection are the leading causes of acute respiratory tract infection in children, and clinical manifestations of these virus infections are considered similar. To investigate the differences in clinical characteristics between HMPV and RSV infections in young children, we prospectively enrolled children <3 years old who required hospitalization with acute respiratory tract infection by HMPV or RSV at 10 hospitals in Japan. We enrolled 48 with HMPV infection and 141 children with RSV infection. Patients with HMPV infection were older than those with RSV infection. High-grade fever was more frequently observed in patients with HMPV infection, whereas no significant differences in respiratory symptoms were apparent. Abnormal serum lactate dehydrogenase values and consolidation shadows on chest X-ray were more frequently observed in patients with HMPV infection. During hospitalization, nasal mucus suction was more frequently required in patients with RSV infection. On the other hand, β2-adr...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research