Racial/Ethnic Variation in Emergency Department Care for Children With Asthma

Conclusions In this study, children from racial/ethnic minority groups had higher odds of steroid administration and lower odds of radiological testing compared with white children. The underlying reasons for these differences are likely multifactorial, including varying levels of disease severity, health literacy, and access to care.
Source: Pediatric Emergency Care - Category: Emergency Medicine Tags: Original Articles Source Type: research

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Toxic air contributes to health conditions such as asthma, cancer and stroke, say expertsFive people die each week in Bristol as a result of high levels of air pollution, a study has revealed.Researchers at King ’s College London examined the combined impact of PM2.5, which is mainly from domestic wood and coal burning and industrial combustion and nitrogen dioxide, which mainly comes from older polluting vehicles.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Air pollution Bristol Environment UK news Science King's College London Education Higher education Cities Source Type: news
In conclusion, oral exposure to low-dose BPA at levels equivalent to human exposure can aggravate allergic asthmatic responses through enhancement of Th2-skewed responses, lung hormone receptor downregulation, and MLN and BM microenvironment change.
Source: Toxicology Reports - Category: Toxicology Source Type: research
ConclusionsAlthough children and adolescents with VACTERL association reported similar HRQoL to those of European children with chronic conditions, their psychological well-being was comparable to Swedish school children in general. Nevertheless, some individuals among both children and parents were in need of extra support. This attained knowledge is valuable when counselling parents regarding the prognosis for children with VACTERL association.
Source: Quality of Life Research - Category: Health Management Source Type: research
This article reviews the latest developments in conditioning regimens for primary immunodeficiency (PID). It focuses on data regarding transplant outcomes according to newer reduced toxicity conditioning regimens used in HCT for PID.Recent FindingsConventional myeloablative conditioning regimens are associated with significant acute toxicities, transplant-related mortality, and late effects such as infertility. Reduced toxicity conditioning regimens have had significant positive impacts on HCT outcome, and there are now well-established strategies in children with PID. Treosulfan has emerged as a promising preparative agen...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Abstract The authors have observed that the function linking health outcomes with exposure to particulate-matter (PM) follows a biphasic pattern. It peaks around levels of PM10≤100 μg/m3, then weakens and rises again at PM10 levels in the range of hundreds. This could be due to a different nature of PM, the first peak reflecting a stronger anthropogenic and the second - weaker non-anthropogenic particles' effect. The current analysis is focused at the biphasic pattern on the association between PM levels with BG and asthma exacerbations. Pollutants were assessed by local monitoring stations and a satelliteba...
Source: Chemosphere - Category: Chemistry Authors: Tags: Chemosphere Source Type: research
Publication date: Available online 16 November 2019Source: Life SciencesAuthor(s): Hui-Mei Wu, Qiu-Meng Xie, Cui-Cui Zhao, Juan Xu, Xiao-Yun Fan, Guang-He FeiAbstractAimsBoth CpG oligodeoxynucleotide (CpG-ODN) and melatonin have been reported to induce Th1 response and contribute to allergic asthma resistance. Here, we aimed to reveal how they confer such effect as well as whether they crosstalk with each other.Main methodsSix-week-old Female C57BL/6 mice were challenged by OVA to induce allergic airway inflammation, and were treated with CpG-ODN, CpG-ODN plus Luzindole or melatonin respectively. Bronchoalveolar lavage flu...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 15 November 2019Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Saurabh B. Ganorkar, Yvan Vander Heyden, Atul A. Shirkhedkar, Deepak K Lokwani, Dinesh M. Dhumal, Preeti S. BobadeAbstractThe obligatory testing of drug molecules and their impurities to protect users against toxic compounds seems to provide interesting opportunities for new drug discovery. Impurities, which proved to be non-toxic, may be explored for their own therapeutic potential and thus be a part of future drug discovery. The essential role of pharmaceutical analysis can thus be extended to achieve th...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
Conclusion: Here we discuss the major implications of these findings for the association between microorganisms and cancer, and also between some immune pathologies, like autoimmune diseases, and cancer.
Source: Current Cancer Therapy Reviews - Category: Cancer & Oncology Source Type: research
We describe the potential benefits of existing asthma and COPD therapies in treating ACO patients, and the value of a “treatable traits” approach to ACO management. Throughout the review, we highlight some of the pressing, unanswered questions surrounding ACO that are relevant to the clinical community. Ultimately, addressing these questions is necessary if we are to improve clinical outcomes for this complex and heterogenous patient population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
A 74-year-old woman with a prior history of tobacco use presented with a chronic cough productive of clear sputum. She carried a diagnosis of asthma for the past 20 years but had minimal improvement in symptoms despite treatment with inhaled corticosteroids and long acting beta agonists. Her medical history was remarkable for gastroesophageal reflux disease that resolved after an esophageal fundoplication.
Source: The American Journal of Medicine - Category: General Medicine Authors: Source Type: research
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