miR-145-5p regulates fibrotic features of recessive dystrophic epidermolysis bullosa skin fibroblasts.

CONCLUSIONS: Our results highlight the pro-fibrotic role of miR-145-5p and its regulatory networks in RDEB, shedding light on novel disease pathomechanisms and targets for future therapeutic approaches. This article is protected by copyright. All rights reserved. PMID: 30816994 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30816994?dopt=Abstract

Source: The British Journal of Dermatology - February 27, 2019 Category: Dermatology Authors: Condorelli AG, Logli E, Cianfarani F, Teson M, Diociaiuti A, El Hachem M, Zambruno G, Castiglia D, Odorisio T Tags: Br J Dermatol Source Type: research