A Standardisation Approach to Compare Treatment Safety and Effectiveness Outcomes between Clinical Trials and Real World Populations in Psoriasis.

CONCLUSIONS: Our results suggest that RCTs of biologic therapies in psoriasis patients are not fully representative of the real-world population, but this lack of external validity does not account for the efficacy-effectiveness gap. This article is protected by copyright. All rights reserved.
PMID: 30822358 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - February 28, 2019 Category: Dermatology Authors: Yiu ZZN, Mason KJ, Barker JNWN, Hampton PJ, McElhone K, Smith CH, Warren RB, Griffiths CEM, Lunt M, Burden AD, BADBIR Study Group Tags: Br J Dermatol Source Type: research