Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development.

CONCLUSION: Collectively, these results support a role of defective cohesin in the development of human colorectal cancer.
PMID: 30823889 [PubMed - in process]

Source: Clinical Colorectal Cancer - February 28, 2019 Category: Cancer & Oncology Authors: Sarogni P, Palumbo O, Servadio A, Astigiano S, D'Alessio B, Gatti V, Cukrov D, Baldari S, Pallotta MM, Aretini P, Dell'Orletta F, Soddu S, Carella M, Toietta G, Barbieri O, Fontanini G, Musio A Tags: J Exp Clin Cancer Res Source Type: research