The RNA binding protein RBMS3 inhibits the metastasis of breast cancer by regulating Twist1 expression.

CONCLUSIONS: In summary, our study revealed a novel mechanism of the RBMS3/Twsit1/MMP2 axis in the regulation of invasion and metastasis of breast cancer, which may become a potential molecular marker for breast cancer treatment.
PMID: 30819235 [PubMed - in process]

Source: Clinical Breast Cancer - February 27, 2019 Category: Cancer & Oncology Authors: Zhu L, Xi PW, Li XX, Sun X, Zhou WB, Xia TS, Shi L, Hu Y, Ding Q, Wei JF Tags: J Exp Clin Cancer Res Source Type: research