Multiscale time-resolved fluorescence study of a glycogen phosphorylase inhibitor combined with quantum chemistry calculations

Phys. Chem. Chem. Phys., 2019, Accepted Manuscript DOI: 10.1039/C8CP07538G, PaperValentin Maffeis, Konstantinos Mavreas, Filippo Monti, Michael Mamais, Thomas Gustavsson, Evangelia D Chrysina, Dimitra Markovitsi, Thanasis Gimisis, Alessandro Venturini A fluorescence study of N1-( β-D-glucopyranosyl)-N4-[2-acridin-9(10H)-onyl]-cytosine (GLAC), the first fluorescent potent inhibitor of Glycogen Phosphorylase (GP), in neutral aqueous solution, is presented herein. Quantum chemistry (TD-DFT) calculations show the existence of... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Phys. Chem. Chem. Phys. latest articles - March 4, 2019 Category: Chemistry Authors: Valentin Maffeis Source Type: research