Genomic testing of a single patient reveals a gene commonly mutated in pediatric melanoma

(St. Jude Children's Research Hospital) Comprehensive clinical genomic testing of an adolescent patient, including whole genome sequencing, helped researchers identify mutations in a single gene that drive the most common childhood melanoma. The St. Jude Children's Research Hospital study appears as an advance online publication today in the journal Nature Medicine.Further research found that 33 percent of young people with spitzoid melanoma screened in this study carried novel mutations, including rearrangements, in the same gene, MAP3K8.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news