nabumetone

Title: nabumetoneCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/1/2019 12:00:00 AM
Source: MedicineNet Arthritis General - Category: Rheumatology Source Type: news

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This article discusses the most common tumor and tumor-like lesions arising at the shoulder. Osseous tumors of the shoulder rank second in incidence to those at the knee joint and include benign osteochondromas and myeloma or primary malignant lesions, such as osteosarcoma or chondrosarcomas. Soft tissue tumors are overwhelmingly benign, with lipomas predominating, although malignant lesions, such as liposarcomas, can occur. Numerous tumor-like lesions may arise from the joints or bursae, due to either underlying arthropathy and synovitis (eg, rheumatoid arthritis and amyloid) or related to conditions, including tenosynovi...
Source: Magnetic Resonance Imaging Clinics of North America - Category: Radiology Authors: Source Type: research
ObjectiveGenetic variants in the region of tumor necrosis factor –induced protein 3–interacting protein 1 (TNIP1) are associated with autoimmune disease and reducedTNIP1 gene expression. The aim of this study was to define the functional genetic mechanisms drivingTNIP1 hypomorphic expression imparted by the systemic lupus erythematosus –associatedTNIP1 H1 risk haplotype.MethodsDual luciferase expression and electrophoretic mobility shift assays were used to evaluate the allelic effects of 11 risk variants on enhancer function and nuclear protein binding in immune cell line models (Epstein ‐Barr virus [E...
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Original Article Source Type: research
This study was undertaken to investigate the relationship of PPM1A to osteoclast differentiation by generating conditional gene‐knockout (PPM1Afl/fl;LysM ‐Cre) mice and evaluating their bone phenotype.MethodsThe bone phenotypes of LysM ‐Cre mice (n = 6) and PPM1Afl/fl;LysM ‐Cre mice (n = 6) were assessed by micro–computed tomography. Osteoclast differentiation was induced by culturing bone marrow–derived macrophages in the presence of RANKL and macrophage colony‐stimulating factor (M‐CSF), and was evaluated by counting tartrate‐resistant acid phosphatase– positive multinucleated cells. Level...
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Original Article Source Type: research
Publication date: Available online 29 March 2020Source: Joint Bone SpineAuthor(s): Olivia Berthoud, Guillaume Coiffier, Jean-David Albert, Anne Gougeon-Jolivet, Claire Goussault, Claude Bendavid, Pascal Guggenbhul
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Condition:   Psoriatic Arthritis Interventions:   Other: General evaluation;   Other: Dermatological evaluation;   Other: Rheumatological evaluation;   Other: para clinical data;   Other: Patient reported outcomes (PROs) Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Arthiritis in Children Intervention:   Other: Observation Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Psoriatic Arthritis Interventions:   Other: General evaluation;   Other: Dermatological evaluation;   Other: Rheumatological evaluation;   Other: para clinical data;   Other: Patient reported outcomes (PROs) Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Arthiritis in Children Intervention:   Other: Observation Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: Our study suggested that quercetin suppresses the migration and invasion of FLSs via regulating the miR-146a/GATA6 axis. PMID: 32216502 [PubMed - as supplied by publisher]
Source: Immunopharmacology and Immunotoxicology - Category: Allergy & Immunology Tags: Immunopharmacol Immunotoxicol Source Type: research
Authors: Chen Y, Xu W, Yang H, Shao M, Xu S, Deng J, Gao X, Liu H, Shuai Z, Xu S, Pan F Abstract Present studies on serum hepcidin levels in patients with rheumatoid arthritis (RA) are inconsistent. We aimed to synthetically evaluate the relationship between hepcidin and RA, and the correlation of serum hepcidin levels and RA disease activity as well as anemia associated with RA. Multiple electronic databases were searched. Pooled standard mean difference (SMD) with 95% confidence interval (CI) and correlation coefficients between hepcidin levels and rheumatoid factor (RF), disease activity for 28 joints (DAS28), a...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
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