Dose Constraint Model to Predict Neuroendocrine Dysfunction in Young Patients with Brain Tumours: Data from a Prospective Study

ConclusionsOur prospective longitudinal study demonstrates feasibility of HPA avoidance using modern high-precision conformal RT techniques and correlates HPA dosimetry with neuroendocrine dysfunction. We suggest restricting HPA dose to <27 Gy to minimize the risk of post-RT neuroendocrine deficits.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research