New IgE immediate hypersensitivity reactions on reintroduction of food restricted for treatment of eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease. Because EoE is largely food driven, elimination diet (ED) is 1 of the 2 primary modalities used to treat EoE1,2 Options include empiric EDs (6, 4, or 2 food EDs) or targeted EDs based on food allergy testing.3,4 Recently, children with EoE have been reported to develop immediate hypersensitivity reactions with reintroduction of previously immunoglobulin E (IgE) tolerated milk.5 –8 Herein, anaphylaxis to previously tolerated wheat in an adult with EoE, and diffuse urticaria from soy reintroduction in a teen with EoE are presented.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research