Chronic spontaneous urticaria and angioedema requiring treatment with omalizumab in a patient with hereditary angioedema

A 27-year-old female patient with a history of hereditary angioedema (HAE), diagnosed at the age of 15 years, is routinely followed-up in Immunology clinic. She initially presented with a 3-year history of recurrent angioedema of the extremities and episodic acute abdominal pain with nausea and vomiting. Although there was no clear family history of HAE, she noted that her father had experienced swelling of the hand years before but had not sought medical attention for this. Both parents were advised to have C1 esterase inhibitor level and function tested however, have not yet done so.

Source: Annals of Allergy, Asthma and Immunology - February 28, 2019 Category: Allergy & Immunology Authors: Susan Tadros, Grant R. Hayman Tags: Clinical Pearls Source Type: research