Noonan's syndrome and cardiac surgery: what can we learn?

Noonan syndrome (NS), and autosomal dominant disorder, is the second most common genetic syndrome associated with congenital heart disease. Over 80% of patients with NS have cardiac involvement and the most common lesions are pulmonary stenosis, atrial septal defects (ASD), and hypertrophic cardiomyopathy (HCM). There clearly is a dearth of data with respect to outcomes after heart surgery for NS patients. The authors from the Mayo Clinic should be congratulated for putting together this valuable information spanning 16 years and including 29 patients.

Source: Seminars in Thoracic and Cardiovascular Surgery - February 28, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Emile Bacha Tags: CONGENITAL – Editorial Commentary Source Type: research