Is There an “Asymptote of Gain” Beyond Which Further Increases in Cardiorespiratory Fitness Convey No Additional Benefits on Mortality and Atrial Fibrillation?

The debate exists on whether the dose-response relationship between physical activity (PA) and mortality benefits is, in fact, a curvilinear, U-shaped, or J-shaped curve.1,2 Cardiorespiratory fitness (fitness), highly reflective of habitual PA, is a strong protector against various adverse health outcomes including cardiovascular disease (CVD)3,4 and is also associated with lower health care costs.5 It has been suggested that high levels of fitness may be at least as important as lower body mass index in the prevention of CVD.

Source: Mayo Clinic Proceedings - March 1, 2019 Category: Internal Medicine Authors: Sae Young Jae, Sudhir Kurl, Hyun Jeong Kim, Barry A. Franklin, Setor K. Kunutsor, Mira Kang, Jari A. Laukkanen Tags: Letter to the editor Source Type: research