Whole organ sheep kidney tissue engineering and in vivo transplantation: Effects of perfusion-based decellularization on vascular integrity.

CONCLUSIONS: This study demonstrated the efficacy of well-preserved acellular scaffold and vasculature network in post renal transplant outcome in a sheep model. These results have potential to pave the road for further investigations in acellular whole organ transplantation.
PMID: 30813040 [PubMed - in process]

Source: Biol Sci Space - March 1, 2019 Category: Science Authors: Kajbafzadeh AM, Khorramirouz R, Nabavizadeh B, Ladi Seyedian SS, Akbarzadeh A, Heidari R, Masoumi A, Azizi B, Seyed Hossein Beigi R Tags: Mater Sci Eng C Mater Biol Appl Source Type: research