Oral hygiene instructions and professional control as part of the treatment of desquamative gingivitis. Systematic review.

CONCLUSIONS: In conclusion the studies presented support the efficacy of maintaining personal and professional oral hygiene in patients with GD, reducing the clinical signs of the disease, regardless of its pathogenesis. PMID: 30818305 [PubMed - in process]
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research

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AbstractHereditary spastic paraplegias (HSP) share as cardinal feature progressive spastic gait disorder. SPG4 accounts for about 25% of cases and is caused by mutations in theSPAST gene. Although HSP is an upper motor neuron disease, the relevance of non-motor symptoms is increasingly recognized because of the potential response to treatment. Our study sets out to evaluate non-motor symptoms and their relevance with regard to health-related quality of life. In 118 genetically confirmed SPG4 cases and age- and gender-matched controls, validated questionnaires were used to evaluate fatigue, depression, pain, and restless le...
Source: Journal of Neurology - Category: Neurology Source Type: research
This study aimed to determine factors that may influence levels of daytime sleepiness and fatigue in a large cohort of DM1 patients followed for 9 years.MethodsThis study included 115 patients with DM1 at baseline (Time 1,T1) and at Time 2 (T2) who were questioned for daytime sleepiness, fatigue, history of depression, psychological distress, pain, hypothyroidism, and sleep habits. Also, their muscular impairment and intellectual quotient were evaluated. Regression models were used to identify correlates of daytime sleepiness and fatigue while controlling for time effect.ResultsBoth daytime sleepiness and fatigue incr...
Source: Journal of Neurology - Category: Neurology Source Type: research
Publication date: Available online 29 January 2020Source: IDCasesAuthor(s): Sunish Shah, Marjorie Golden, Jeffrey E. Topal, Dayna McManusAbstractA 78 year old man developed a methicillin sensitive Staphylococcus aureus (MSSA) post-operative wound infection following an elective L2-L4 laminectomy. He was treated with surgical debridement which was to be followed by a planned 6 weeks course of cefazolin. However, two weeks post debridement, a follow-up MRI revealed an L3-L5 epidural abscess, septic arthritis and vertebral osteomyelitis prompting repeat surgical debridement. No purulence was noted, and operative cultur...
Source: IDCases - Category: Infectious Diseases Source Type: research
The objective of this study was to prospectively test the performance of POC cTn measurement by paramedics to detect myocardial infarction (MI) among patients transported to the ED for acute chest pain.Methods: A prospective cohort study of adults with non-traumatic chest pain was conducted in 3 Emergency Medical Services agencies (12/2016-1/2018). Patients with ST-elevation MI on ECG were excluded. During ambulance transport paramedics initiated intravenous access, collected blood, and used a POC device (i-STAT; Abbott Laboratories) to measure cTn. Following ED arrival, participants received standard evaluations including...
Source: Prehospital Emergency Care - Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research
Publication date: Available online 28 January 2020Source: NeuroscienceAuthor(s): Abigail Hellman, Teresa Maietta, Kanakaharini Byraju, Yunseo Linda Park, Andrea Liss, Tarun Prabhala, Paul Neubauer, Emery Williams, Clif Burdette, Damian S. Shin, Goutam Ghoshal, Julia Nalwalk, Aira Agrawal, Jiang Qian, Julie PilitsisAbstractNon-invasive treatment methods for neuropathic pain are lacking. We assess how modulatory low intensity focused ultrasound (liFUS) at the L5 dorsal root ganglion (DRG) affects behavioral responses and sensory nerve action potentials (SNAPs) in a common peroneal nerve injury (CPNI) model. Rats were assesse...
Source: Neuroscience - Category: Neuroscience Source Type: research
Authors: Wang Y, Wang M, Ni Y, Liang Z Abstract Background: Venous thromboembolism (VTE) is a common complication in cancer patients. We aim to evaluate the effect and safety of direct oral anticoagulants (DOACs) as primary prophylaxis in ambulatory cancer patients.Methods: We conducted a literature search in PubMed, EMBASE and ClinicalTrials for studies that evaluated DOACs for thromboprophylaxis in cancer patients. RevMan 5.3 software was used for this meta-analysis.Results: Three randomized controlled trials (RCTs) with a total of 1465 patients were pooled in the meta-analysis. DOACs significantly reduced the sy...
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
We report the case of a 6-year-old girl who presented with generalized abdominal pain and flu-like symptoms. Blood tests and AUS revealed typical findings of AP and a nasopharyngeal aspirate was positive for IVA. Twenty-four hours later, the patient developed signs of acute appendicitis, which was also confirmed by AUS. This case highlights the importance of AUS in the management of acute abdominal conditions in children, including reactive entities such as appendicitis, as well as the need to consider IVA as a potential causal agent of AP. PMID: 31985255 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Publication date: 15 April 2020Source: Journal of Molecular Structure, Volume 1206Author(s): V. Porchezhiyan, D. Kalaivani, J. Shobana, S.E. NoorjahanAbstractUnsymmetrical 1,3-diketones with potential anti-cancer as well as anti-inflammatory activities were synthesized via direct coupling reaction between ketones and N-acyl benzotriazoles, based on soft enolisation under mild conditions and characterized by 1H,13C NMR, IR and HRMS. Molecular docking of the synthesized compounds (5a-5j) with the enzymes PTK6 (breast cancer cell), COX-1 and COX-2 (inflammation and pain) revealed 5j to be the potent compound. It was found to ...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
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