DNA methylation of the NR3C1 promoter region in brains of pediatric victims of physical abuse.

We examined DNA methylation of the 1F promoter region of NR3C1 in the postmortem brains of eight children including four ELS cases. As a result, DNA methylation was evident in ELS cases due to severe physical abuse. Epigenetic status may have potential application as a biomarker for clarifying the antemortem experiences of deceased. PMID: 30810493 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30810493?dopt=Abstract

Source: Neurocase - February 27, 2019 Category: Neurology Authors: Takahashi Y, Kubo R, Sano R, Kuninaka H, Murayama M, Hayakawa A, Kominato Y Tags: Neurocase Source Type: research