Mechanisms Underlying the Contribution of Sleep Disturbances to Pain (R01 Clinical Trial Optional)

Funding Opportunity PA-19-200 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to encourage mechanistic research to investigate the impact of sleep disturbances on pain. The mechanisms and processes underlying the contribution of sleep and sleep disturbances to pain perception and the development and maintenance of chronic pain may be very broad. This FOA encourages interdisciplinary research collaborations by experts from multiple fieldsneuroscientists, psychologists, endocrinologists, immunologists, geneticists, pharmacologists, chemists, physicists, behavioral scientists, clinicians, caregivers, and others in relevant fields of inquiry.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding

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Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Exercise and Fitness Health Mental Health Stress Source Type: blogs
The National Center for Complementary and Integrative Health presents the inaugural lecture in a series, “ Novel Approaches at the Intersection of Mental Health and Pain, ” part of the Center ’ s Integrative Medicine Research Lecture Series: Lighting Up Our Lives: How Light Influences Our Mental and Physical Health Helen Burgess, Ph.D., University of Michigan Natural outdoor light and artificial indoor light can affect our mental and physical health. This is especially relevant in the current times when we are asked to stay home and spend less time outside. Dr. Burgess will examine how light reaches the ...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
In this study, we evaluated the effects of perioperative dexmedetomidine infusion on postoperative analgesia in patients undergoing lateral thoracotomy for thoracic esophageal cancer. Methods: A total of 62 patients undergoing lateral thoracotomy for thoracic esophageal cancer were randomized to receive adjuvant therapy with either dexmedetomidine (0.5 μg/kg intravenous bolus injection for 10 min before induction of anesthesia, followed by continuous infusion of 0.2-0.4 μg/kg/h until the end of surgery, and 0.06 μg/kg/h for 5 days after surgery) or equal volumes of saline. Acute po...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
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Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
We examined seasonal variation in pain severity and pain dissemination, as well as in pain-associated conditions, such as sleep impairment, sleep timing, mental distress, fatigue and physical activity. We also examined if any of these associated conditions moderated the seasonality in pain. This prospective study was conducted in the subarctic municipality of Tromsø, Norway (69º North), on a sample of patients with chronic musculoskeletal pain (N = 56). Data were collected with self-report questionnaires and objective actigraphy measures (7 days) twice: winter and summer. Mixed linear regression model...
Source: Chronobiology International - Category: Biology Authors: Tags: Chronobiol Int Source Type: research
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Addiction Marijuana Mental Health Source Type: blogs
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Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Tags: Correspondence Source Type: research
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Healthy Aging Managing your health care Memory Neurological conditions Prevention Surgery Source Type: blogs
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Source: Pain - Category: Anesthesiology Tags: Comprehensive Review Source Type: research
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