Dissecting cause from consequence: a systematic approach to thermal limits COMMENTARY

Heath A. MacMillan Thermal limits mark the boundaries of ectotherm performance, and are increasingly appreciated as strong correlates and possible determinants of animal distribution patterns. The mechanisms setting the thermal limits of ectothermic animals are under active study and rigorous debate as we try to reconcile new observations in the lab and field with the knowledge gained from a long history of research on thermal adaptation. Here, I provide a perspective on our divided understanding of the mechanisms setting thermal limits of ectothermic animals. I focus primarily on the fundamental differences between high and low temperatures, and how animal form and environment can place different constraints on different taxa. Together, complexity and variation in animal form drive complexity in the interactions within and among levels of biological organization, creating a formidable barrier to determining mechanistic cause and effect at thermal limits. Progress in our understanding of thermal limits will require extensive collaboration and systematic approaches that embrace this complexity and allow us to separate the causes of failure from the physiological consequences that can quickly follow. I argue that by building integrative models that explain causal links among multiple organ systems, we can more quickly arrive at a holistic understanding of the varied challenges facing animals at extreme temperatures.
Source: Journal of Experimental Biology - Category: Biology Authors: Tags: Ecophysiology: responses to environmental stressors and change COMMENTARY Source Type: research

Related Links:

CONCLUSION: The results of this study showed no significant relationships between MMR protein expression and recurrence rates or overall survival in patients with GBM. PMID: 31529454 [PubMed - in process]
Source: Turkish Neurosurgery - Category: Neurosurgery Authors: Tags: Turk Neurosurg Source Type: research
CONCLUSION: Although PS being a clinical diagnosis, this study indicated that in patients whom PS was not suspected at the initial examination, 8.2% of them were finally diagnosed after MRI evaluations. Performing specific pelvic sequences as an adjunct to routine lumbar MRI can salvage underdiagnosed patients with PS and facilitate early detection of this pathological condition. PMID: 31529453 [PubMed - in process]
Source: Turkish Neurosurgery - Category: Neurosurgery Authors: Tags: Turk Neurosurg Source Type: research
       
Source: The Commonwealth Fund: Blog - Category: International Medicine & Public Health Authors: Source Type: blogs
In the article “Concussion Biomarkers Assessed in Collegiate Student-Athletes (BASICS) I: Normative study”, Asken et al. measured various concussion-related serum biomarkers in 415 nonconcussed collegiate athletes without recent exposure to head imp...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: Concussions are common among youth athletes. Responsibility for the recognition and management of concussion is often put on coaches. To equip coaches with appropriate knowledge and skills, the US Centers for Disease Control and Prevention (CDC...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
The purpose of this study was to examine the effects of protective football headgear on peripheral vision reaction time and visual target detection. Twenty-five Division I NCAA football players (age = 20.5 yrs ± 0.9, height = 185.9 cm ± 6.8, body mass = ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Sexual assault is a major concern on college campuses. Some colleges and universities adopt and educate their students using an affirmative consent standard, such that for a sexual encounter to be considered consensual (and thus not an act of sexual assaul...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
STUDY DESIGN: Prospective cohort study. BACKGROUND: Pain during Functional Movement Screen (FMS) testing is common and has a significant effect on FMS scoring but the effect on FMS injury risk predictions is unknown. OBJECTIVES: Describe th...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
This study aimed to investigate the frequency of unhealthy and high-risk behaviors and their relationship with demographic features in adolescents living...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
To the Editor Early intervention in health settings is urgently needed to address intimate partner violence (IPV), yet little evidence of effective IPV nursing interventions exists globally. The clinical trial by Dr Jack and colleagues aimed to improve ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
More News: Biology | Environmental Health | Study