Effects of zoledronate on the radiation-induced collagen breakdown: a prospective randomized clinical trial

Conclusion The results indicate the ability of zoledronate to prevent the early radiation-induced bone collagen degradation suggesting that the radiation-induced bone loss is mainly caused by osteoclastic bone resorption rather than by a direct radiation-induced damage.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research