MicroRNA-370 Regulates Cellepithelial-Mesenchymal Transition, Migration, Invasion, and Prognosis of Hepatocellular Carcinoma by Targeting GUCD1.

CONCLUSION: Taken together, our study confirmed that miR-370 suppressed HCC cell metastasis and EMT via regulating GUCD1. Accordingly, the miR-370/GUCD1 axis may potentially acts as attractive therapeutic targets and novel biomarkers for HCC treatment.
PMID: 30799589 [PubMed - in process]

Source: Yonsei Medical Journal - February 28, 2019 Category: Universities & Medical Training Authors: He Y, He X Tags: Yonsei Med J Source Type: research