Circulating vaccine-derived poliovirus type 1 – Indonesia

On 12 February, a circulating vaccine-derived poliovirus type 1 (cVDPV1) has been confirmed in Papua province, Indonesia. Two genetically-linked VDPV1 viruses were isolated from a child with acute flaccid paralysis (AFP) with onset of paralysis on 27 November 2018 and in a healthy community contact, a child whose stool sample was collected on 24 January 2019. The location of this healthy child, with the VDPV isolation, is in a remote village, approximately 3 –4 km away from the AFP case with onset of paralysis on 27 November 2018. Even though this province shares a border with Papua New Guinea, this outbreak is not linked to the cVDPV1 outbreak currently affecting its neighbouring country. WHO and partners are supporting the Ministry of Health (MoH) and local public health authorities in conducting a field investigation, a thorough risk assessment and planning an outbreak response. The exact extent and timing of the outbreak response is being finalized. Initial outbreak response immunization (ORI) has been conducted in Yahukimo district and 5718 children under 15 years of age have been immunized with bivalent oral polio vaccine (bOPV). Disease surveillance, including conducting retrospective and active searches for additional acute flaccid paralysis (AFP) cases, has been further strengthened in community health centres, hospitals and other health facilities including all districts and cities in Papua province. Surveillance has also been strengthened at entry and exit po...
Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: news Source Type: news

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On 23 May 2019, WHO received notification through the Global Polio Laboratory Network (GPLN) of the detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) from an environmental sample collected on 20 April 2019 in a hospital in Northern Cameroon which borders Borno state in Nigeria and Chad.
Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: news Source Type: news
This study is registered with EudraCT, number 2017-000908-21 and ClinicalTrials.gov, number NCT03430349.FindingsBetween May 22 and Aug 22, 2017, 48 volunteers were screened, of whom 15 (31%) volunteers were excluded for reasons relating to the inclusion or exclusion criteria, three (6%) volunteers were not treated because of restrictions to the number of participants in each group, and 30 (63%) volunteers were sequentially allocated to groups (15 participants per group). Both novel OPV2 candidates were immunogenic and increased the median blood titre of serum neutralising antibodies; all participants were seroprotected aft...
Source: The Lancet - Category: General Medicine Source Type: research
This report describes global progress toward poliomyelitis eradication during January 1, 2017-March 31, 2019, and updates previous reports (1,2). Afghanistan and Pakistan reported their lowest annual number of WPV cases (22) in 2017; however, 33 WPV1 cases were reported in 2018. During January-March 2019 (as of May 3), 12 WPV1 cases had been reported worldwide, four more than the eight reported during the corresponding period in 2018. The occurrence of polio cases caused by circulating vaccine-derived poliovirus (cVDPV) is rare and occurs where oral poliovirus vaccine (OPV) coverage has been low and vaccine virus reverts t...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
 Washington – There were at least 973 attacks on health workers, health facilities, health transports and patients in 23 countries in conflict in 2018, the Safeguarding Health in Conflict Coalition reported today. At least 167 health workers died and at least 710 were injured. This marks an increase in the number of documented attacks compared to 2017, when the Coalition reported 701 such instances. The Coalition’s sixth annual report documents attacks on vaccination workers, paramedics, nurses, doctors, midwives, community volunteers, drivers and guards, in violation of international norms and i...
Source: Doctors of the World News - Category: International Medicine & Public Health Authors: Tags: Uncategorised Source Type: news
[Daily Trust] The Ogun State Commissioner for Health, Dr Babatunde Ipaye, says about 1.2 million children under the age of five are expected to be immunise during the ongoing Outbreak Response (OBR) campaign. He spoke yesterday while monitoring the OBR campaign against the circulating vaccination derived polio virus in the southwest,t at Imoba Community in Ifo Local Government Area of the st.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Publication date: Available online 16 May 2019Source: The LancetAuthor(s): Cynthia J Snider, Khalequ Zaman, Concepcion F Estivariz, Mohammad Yunus, William C Weldon, Kathleen A Wannemuehler, M Steven Oberste, Mark A Pallansch, Steven GF Wassilak, Tajul Islam A Bari, Abhijeet AnandSummaryBackgroundIntradermal administration of fractional inactivated poliovirus vaccine (fIPV) is a dose-sparing alternative to the intramuscular full dose. We aimed to compare the immunogenicity of two fIPV doses versus one IPV dose for routine immunisation, and also assessed the immunogenicity of an fIPV booster dose for an outbreak response.Me...
Source: The Lancet - Category: General Medicine Source Type: research
[Thomson Reuters Foundation] New York -Documented attacks on health workers in conflict areas increased dramatically last year, endangering both children waiting for polio vaccines and efforts to contain the latest outbreak of Ebola, research showed on Wednesday.
Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news
A set of  measles outbreaks in Washington state, New York City, and elsewhere, is making national headlines and frightening parents around the United States. Counter-intuitively, measles making the news is a sign of progress. Not long ago, measles was so common that it was simply not newsworthy. Suffer ing from the extremely infectious disease, which causes spotty rashes and a hacking cough, was widespread and often deadly.It was once the case that even royalty fell victim to diseases now easily preventable with routine shots given during childhood.  Measles killed the un-vaccin...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
May 14, 2019 WashingtonThere were at least 973 attacks on health workers, health facilities, health transports, and patients in 23 countries in conflict in 2018, the  Safeguarding Health in Conflict Coalition reported today. At least 167 health workers died and at least 710 were injured. This marks an increase in the number of documented attacks compared to 2017, when the coalition reported 701 such instances.The coalition ’s sixth annual report documents attacks on vaccination workers, paramedics, nurses, doctors, midwives, community volunteers, drivers, and guards, in violation of international norms an...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Safeguarding Health in Conflict Coalition Policy & Advocacy Source Type: news
(VANCOUVER, Wash.) — Parents in Washington state will no longer be able to claim a personal or philosophical exemption for their children from receiving the combined measles, mumps and rubella vaccine before attending a day care center or school under a measure signed Friday by Gov. Jay Inslee. The state saw more than 70 cases of measles this year, and Inslee signed the bill at Vancouver City Hall, in the county where most of those cases were centered. The new law takes effect at the end of July. Inslee said that while the bill was an important step in public health, he warned it doesn’t do “everything ne...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized measles onetime washington Source Type: news
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